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As we set our clocks back in an annual return to standard time, its not just our clocks that need some tuning. Is it possible that our skin has an internal clock? And if it does, can the clock break? The main function of human skin is to protect our internal organs from the potential dangers of the external elements. Our skin adjusts to environmental factors, including UV radiation from the sun, pathogens, wind, heat, cold, and anything else thrown at us, by having an internal biological clock which follows circadian rhythms. Janich and colleagues have published a study in the journal of Nature (2011) and a follow up study in the journal Cell Stem Cell (2013) showing that daily regeneration of skin is time-dependent. Circadian rhythms control precise timing of skin cells’ behavior during the 24 hour day period. When the sunlight is at its peak, human stem cells protect themselves against radiation-induced DNA damage by activating the genes involved in UV protection at that time of the day. At night stem cells divide and regenerate, replacing damaged cells with healthy ones. However, if there is a disruption of circadian rhythm, the stem cells accumulate DNA damage, which leads to premature aging and cancer development. With aging our circadian clock loses its accuracy, causing failure for our cells to regenerate, leading to greater potential for tumor development. So what can we do? Knowing that the skin changes in appearance from day to night can help us use the skin’s circadian rhythms to our advantage. Using NuVsio Mineral Enriched Balm Concentrate in the morning boosts the skin’s levels of natural antioxidant protection against sun’s UV radiation and other environmental factors. The night application helps regenerate the damaged skin cells and provides hydration. It is also important to get 7-8 hours of sleep to give the skin time to repair itself at night, at least on the weekends.

Wishing you a healthy, glowing skin,


Dr. Brei, PhD NuVsio Founder